In short: Epithalon (also written Epitalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly (AEDG), modelled on a pineal-gland peptide, supplied by Vexar Lab strictly for in-vitro laboratory research and not approved for human consumption. It is a widely cited tool compound in telomere and longevity research. Before ordering any peptide, research buyers should confirm purity of at least 99% by HPLC, identity confirmation by mass spectrometry, and clear batch numbering with a corresponding certificate of analysis (COA).
What is Epithalon?
Epithalon is a short four-amino-acid peptide bioregulator (Ala-Glu-Asp-Gly) developed by Vladimir Khavinson and colleagues, derived from study of the pineal extract epithalamin. As one of the simplest synthetic peptide bioregulators, it is often used as a reference compound in research on short peptides that are proposed to interact with DNA and gene-regulatory processes. Much of the foundational work was conducted at the St. Petersburg Institute of Bioregulation and Gerontology, with independent laboratories more recently revisiting its reported effects.
What does the research investigate?
In cell-culture and animal models, epithalon has been studied chiefly for reported activation of telomerase and telomere elongation in somatic cells, for effects on pineal melatonin rhythm and circadian function, and for changes in lifespan and age-related markers in model organisms. Some animal studies report extended lifespan without increased tumour incidence, and the literature also describes effects on immune-related signalling and various enzyme activities. The precise mechanisms remain uncertain and these are investigational pre-clinical findings that do not establish human safety or efficacy. Always read the primary sources directly.
Purity and quality: what research buyers should check
- Purity of at least 99% by HPLC — confirm the figure against the batch-specific COA rather than a generic specification sheet.
- Identity confirmation by mass spectrometry — the measured mass should match the expected molecular weight of the peptide.
- Batch numbering — every vial should trace back to a documented production batch and its analytical records.
Vexar Lab supplies Epithalon as a pack of 10 vials, ≥99% HPLC-verified, batch-numbered, with mass-spec confirmation.
Handling and storage
Epithalon is supplied lyophilised. Standard laboratory practice for lyophilised peptides applies: store the sealed vials cold and protected from light, reconstitute only with an appropriate sterile solvent immediately before use, and aliquot to avoid repeated freeze-thaw cycles. Reconstituted peptide is generally less stable than the dry powder and should be kept refrigerated and used within a short working window. Follow your own institution’s handling protocols.
Wholesale supply
Vexar Lab supplies Epithalon to research buyers and resellers in packs of 10 vials, with a £300 minimum order, bulk pricing on volume, £45 flat worldwide shipping, and optional custom labelling for resellers.
Frequently asked questions
Is Epithalon approved for human use?
No. Vexar Lab supplies epithalon strictly as a research material for in-vitro laboratory use. It is not sold for human consumption, and nothing here constitutes medical or dosing guidance.
What purity does Vexar Lab guarantee?
Each batch is verified at ≥99% by HPLC with identity confirmed by mass spectrometry, and every vial is batch-numbered against its COA.
How is it shipped and packaged?
It ships lyophilised in packs of 10 vials, with £45 flat worldwide shipping and batch documentation available on request.
This guide is provided for research-only purposes. Epithalon is supplied strictly for in-vitro laboratory research and is not approved for human consumption. No medical, therapeutic, or dosing advice is given or implied.
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