In short: Survodutide (also designated BI 456906) is a synthetic dual glucagon and GLP-1 receptor agonist peptide and an unapproved investigational compound, supplied strictly for in-vitro laboratory research and not approved for human consumption. It serves as a reference compound in metabolic receptor-signalling studies. Research buyers should require ≥99% purity by HPLC, identity confirmation by mass spectrometry, and clear batch numbering.
What is Survodutide?
Survodutide is a 29-amino-acid peptide based on glucagon, engineered with several substitutions drawn from GLP-1 and exendin-4 and a C18 fatty-diacid chain that, in pharmacological studies, supports an extended half-life. It was developed by Boehringer Ingelheim and Zealand Pharma as a dual agonist of the glucagon and GLP-1 receptors. As an investigational drug candidate that has been studied in clinical trials for metabolic conditions, it is not an approved medicine and is offered here only as a laboratory reference material.
What does the research investigate?
Pre-clinical and early-phase studies have explored how survodutide engages the glucagon receptor and the GLP-1 receptor, and how this dual activity relates to energy expenditure, food-intake signalling and hepatic metabolism in cell and animal models. Some work has examined neuronal regions associated with appetite regulation. Because survodutide remains an unapproved investigational compound, these findings are exploratory and do not establish human safety or efficacy. Always read the primary sources directly.
Purity and quality: what research buyers should check
- ≥99% purity by HPLC (confirm via the batch certificate of analysis, or COA)
- Identity confirmed by mass spectrometry
- Batch numbering for full traceability
Vexar Lab supplies Survodutide as a pack of 10 vials, ≥99% HPLC-verified, batch-numbered, with mass-spec confirmation.
Handling and storage
Standard lyophilised-peptide practice applies. Store sealed vials at -20°C, protected from light and moisture. After reconstitution with an appropriate sterile diluent, keep refrigerated at 2–8°C and use within the period indicated by your protocol. Avoid repeated freeze–thaw cycles, which degrade peptide integrity, and allow vials to reach room temperature before opening to limit condensation.
Wholesale supply
Vexar Lab supplies research peptides in packs of 10 vials, with a £300 minimum order, bulk pricing on volume, £45 flat worldwide shipping, and optional custom labelling for resellers.
Frequently asked questions
Is Survodutide approved for human use?
No. Survodutide is an unapproved investigational compound and is not authorised for human consumption or therapeutic use. Vexar Lab supplies it solely for in-vitro laboratory research.
What makes Survodutide a “dual agonist”?
Its glucagon-based sequence is modified to activate both the glucagon receptor and the GLP-1 receptor, which is why it is studied as a model dual-receptor metabolic peptide.
What purity should research-grade Survodutide meet?
Look for ≥99% by HPLC with a batch COA and mass-spec identity confirmation to ensure traceable, reproducible results.
This guide is for laboratory research reference only. Survodutide is supplied strictly for in-vitro research use and is not for human or animal consumption, nor for any diagnostic or therapeutic application.
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