In short: AOD-9604 is a synthetic peptide derived from the C-terminal region of human growth hormone, studied in pre-clinical models for fat-metabolism signalling. It is supplied strictly for in-vitro laboratory research and is not approved for human consumption. Research buyers should confirm any material against three criteria before purchase: ≥99% purity by HPLC, identity confirmed by mass spectrometry, and clear batch numbering tied to a certificate of analysis.
What is AOD-9604?
AOD-9604 is a synthetic peptide engineered from the C-terminal segment of human growth hormone (approximately amino acids 177–191), an optimised analogue of the HGH fragment 176–191. It is handled in the laboratory as a lyophilised powder reconstituted for in-vitro assay work. Unlike full-length growth hormone, the fragment was designed in research settings to isolate a lipolytic domain.
What does the research investigate?
Pre-clinical research into AOD-9604 has examined lipolysis (fat breakdown) and lipogenesis (fat storage) in adipocyte and obese-animal models, with reports that it influenced fat metabolism without binding the GH receptor or raising IGF-1 in those models. A proposed mechanism involves β3-adrenergic receptor signalling. It is worth noting that later human obesity trials did not demonstrate statistically significant weight-loss outcomes, underscoring that animal findings do not establish human safety or efficacy. Always read the primary sources directly.
Purity and quality: what research buyers should check
- ≥99% purity by HPLC — confirm via the batch certificate of analysis (COA).
- Identity confirmed by mass spectrometry against the expected peptide mass.
- Batch numbering that ties each vial to its COA for traceability.
Vexar Lab supplies AOD-9604 as a pack of 10 vials, ≥99% HPLC-verified, batch-numbered, with mass-spec confirmation.
Handling and storage
Standard lyophilised-peptide practice applies. Store sealed vials of lyophilised powder at -20°C, away from light and moisture. After reconstitution with a suitable solvent, refrigerate and use within a short working window, avoiding repeated freeze-thaw cycles that can degrade peptide integrity. Allow vials to reach room temperature before opening to limit condensation.
Wholesale supply
Vexar Lab supplies research peptides in packs of 10 vials, £300 minimum order, with bulk pricing on volume, £45 flat worldwide shipping, and optional custom labelling for resellers.
Frequently asked questions
Is AOD-9604 approved for human use?
No. AOD-9604 is supplied strictly for in-vitro laboratory research and is not approved for human consumption or any therapeutic use.
Does AOD-9604 raise IGF-1?
In pre-clinical models it was reported to act without binding the GH receptor or elevating IGF-1, but these are animal/cell findings and not human outcomes.
How should purity be verified?
Request the batch certificate of analysis showing ≥99% purity by HPLC and a mass-spectrometry identity confirmation tied to the vial’s batch number.
This guide is provided for informational purposes only. AOD-9604 is sold strictly as a research-only chemical for in-vitro laboratory use and is not for human or veterinary consumption, diagnosis, or treatment.
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