Mazdutide Research Peptide

In short: Mazdutide (also designated IBI362 / LY3305677) is a synthetic dual GLP-1 and glucagon receptor agonist peptide and an investigational compound, supplied strictly for in-vitro laboratory research and not approved for human consumption in the contexts addressed here. It serves as a reference material in metabolic receptor-signalling studies. Research buyers should require ≥99% purity by HPLC, identity confirmation by mass spectrometry, and clear batch numbering.

What is Mazdutide?

Mazdutide is a once-weekly peptide modelled on oxyntomodulin, a natural gut hormone, and engineered to act on both the GLP-1 receptor and the glucagon receptor. Its design aims to balance activation of the two receptors so that GLP-1 effects are retained while glucagon-driven changes are managed. It has been studied in clinical trials for metabolic conditions and remains investigational in most jurisdictions; any regional regulatory approvals do not authorise its use as a research chemical. Vexar Lab supplies it only as a laboratory reference material.

What does the research investigate?

Pre-clinical and early-phase studies have examined how mazdutide’s balanced GLP-1/glucagon receptor activity relates to energy metabolism, glucose handling and body-composition endpoints in cell and animal models, with some multi-omics work exploring metabolic signalling pathways. As an investigational compound, these observations are exploratory and do not establish human safety or efficacy outside controlled, approved clinical settings. Always read the primary sources directly.

Purity and quality: what research buyers should check

≥99% purity by HPLC (confirm via the batch certificate of analysis, or COA)
Identity confirmed by mass spectrometry
Batch numbering for full traceability

Vexar Lab supplies Mazdutide as a pack of 10 vials, ≥99% HPLC-verified, batch-numbered, with mass-spec confirmation.

Handling and storage

Standard lyophilised-peptide practice applies. Store sealed vials at -20°C, protected from light and moisture. After reconstitution with an appropriate sterile diluent, keep refrigerated at 2–8°C and use within the period indicated by your protocol. Avoid repeated freeze–thaw cycles, which degrade peptide integrity, and allow vials to reach room temperature before opening to limit condensation.

Wholesale supply

Vexar Lab supplies research peptides in packs of 10 vials, with a £300 minimum order, bulk pricing on volume, £45 flat worldwide shipping, and optional custom labelling for resellers.

Frequently asked questions

Is Mazdutide approved for human use?

No. For the purposes of this supply, mazdutide is treated as an unapproved investigational compound and is not authorised for human consumption or therapeutic use. Vexar Lab supplies it solely for in-vitro laboratory research.

How does Mazdutide differ from single-target GLP-1 peptides?

It is a dual agonist designed on oxyntomodulin to engage both the GLP-1 and glucagon receptors, which is why it is studied as a model dual-receptor metabolic peptide.

What purity should research-grade Mazdutide meet?

Look for ≥99% by HPLC with a batch COA and mass-spec identity confirmation to ensure traceable, reproducible results.

This guide is for laboratory research reference only. Mazdutide is supplied strictly for in-vitro research use and is not for human or animal consumption, nor for any diagnostic or therapeutic application.